Identifiability Results for Several Classes of Linear Compartment Models

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Identifiability Results for Several Classes of Linear Compartment Models.

Identifiability concerns finding which unknown parameters of a model can be estimated, uniquely or otherwise, from given input-output data. If some subset of the parameters of a model cannot be determined given input-output data, then we say the model is unidentifiable. In this work, we study linear compartment models, which are a class of biological models commonly used in pharmacokinetics, ph...

متن کامل

Identifiability of Linear Compartment Models: the Singular Locus

This work addresses the problem of identifiability, that is, the question of whether parameters can be recovered from data, for linear compartment models. Using standard differential algebra techniques, the question of whether a given model is generically locally identifiable is equivalent to asking whether the Jacobian matrix of a certain coefficient map, arising from input-output equations, i...

متن کامل

Identifiability in linear mixed effects models

In mixed effects model, observations are a function of fixed and random effects and an error term. This structure determines a very specific structure for the variances and covariances of these observations. Unfortunately, the specific parameters of this variance/covariance structure might not be identifiable. Nonidentifiability can lead to complications in numerical estimation algorithms or wo...

متن کامل

Identifiable reparametrizations of linear compartment models

Structural identifiability concerns finding which unknown parameters of a model can be quantified from given input-output data. Many linear ODE models, used in systems biology and pharmacokinetics, are unidentifiable, which means that parameters can take on an infinite number of values and yet yield the same input-output data. We use commutative algebra and graph theory to study a particular cl...

متن کامل

Several Classes of $p$-ary Linear Codes with Few Weights

Few weights codes have been an important topic of coding theory for decades. In this paper, a class of two-weight and three-weight codes for the homogeneous metric over the chain ring R = Fp + uFp + · · ·+ uFp are constructed. These codes are defined as trace codes. They are shown to be abelian. Their homogeneous weight distributions are computed by using exponential sums. In particular, we giv...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Bulletin of Mathematical Biology

سال: 2015

ISSN: 0092-8240,1522-9602

DOI: 10.1007/s11538-015-0098-0